Pakarian, P. and Pawelek, P.D. (2016) "A novel set of vectors for Fur-controlled protein expression under iron deprivation in Escherichia coli." BMC Biotechnology, 16(1):68. doi: 10.1186/s12896-016-0298-1. [Pubmed]

Pakarian, P. and Pawelek, P.D. (2016) "Intracellular co-localization of the Escherichia coli enterobactin biosynthetic enzymes EntA, EntB, and EntE." Biochemical and Biophysical Research Communications, 478 25-32. [Pubmed]

Pakarian, P. and Pawelek, P.D. (2016) "Subunit orientation in the Escherichia coli enterobactin biosynthetic EntA-EntE complex revealed by a two-hybrid approach." Biochimie, 127 1-9. [Pubmed]

Khalil, S., Jaworski, I. and Pawelek, P.D. (2014) “Identification of a surface glutamine residue (Q64) of Escherichia coli EntA required for interaction with EntE.” Biochemical and Biophysical Research Communications, 453 625-630. [Pubmed]

Foshag, D., Campbell, C., and Pawelek, P.D. (2014) "The C-glycosyltransferase IroB from Pathogenic Escherichia coli: Identification of Residues Required for Efficient Catalysis" Biochimica et Biophysica Acta: Proteins and Proteomics, 1844 1619-1630. [Pubmed]

Khalil, S., and Pawelek, P.D. (2011) “Enzymatic Adenylation of 2,3-Dihydroxybenzoate is Enhanced by a Protein-Protein Interaction Between Escherichia coli 2,3-Dihydro-2,3-Dihydroxybenzoate Dehydrogenase (EntA) and 2,3-Dihydroxybenzoate-AMP Ligase (EntE)” Biochemistry, 50 533-545. [Pubmed]

Khalil, S., and Pawelek, P.D. (2009) “Ligand-induced Conformational Rearrangements Promote Interaction Between the Escherichia coli Enterobactin Biosynthetic Proteins EntE and EntB.” Journal of Molecular Biology, 393 658-671. [Pubmed]

Massé, E., and Pawelek, P.D. (2009) “Iron as Nutrient: Strategies for Iron Acquisition and Usage by Pathogenic Microorganisms.” Book chapter in “Iron Deficiency and Overload: From Basic Biology to Clinical Medicine (Nutrition and Health)” Shlomo Yehuda & David I. Mostofsky (Eds). Humana Press (ISBN: 1934115223)

Selected Past Publications

Pawelek, P.D., Croteau, N., Ng-Thow-Hing, C., Khursigara, C.M., Moiseeva, N., Allaire, M., and Coulton, J.W. (2006) “Structure of TonB in Complex with FhuA, E. coli Outer Membrane Receptor.” Science, 312 1399-1402.

Pawelek, P.D., Cheah, J., Coulombe, R., Macheroux, P., Ghisla, S., and Vrielink, A. (2000) “The Structure of L-amino acid Oxidase Reveals the Substrate Trajectory into an Enantiomerically Conserved Active Site.” EMBO Journal, 19 4204-15.

Pawelek, P.D., and MacKenzie, R.E. (1998) “Methenyltetrahydrofolate Cyclohydrolase is Rate Limiting for the Enzymatic Conversion of 10-formyltetrahydrofolate to 5,10-methylenetetrahydrofolate in Bifunctional Dehydrogenase-Cyclohydrolase Enzymes.”  Biochemistry, 37 1109-15.

Publications from the Pawelek Lab